We know one team will be mi sing their top running back this week, but several others are also dealing with uncertain backfields heading into Week 6 play. But the biggest injuries of the week could be to quarterbacks.Dolphins quarterback was downgraded to a limited practice on Friday due to an injury to his right shoulder, and he was listed as questionable on the team's final injury report. Late-week downgrades are never a good sign, and if he can't go, the team would be forced to turn to against and company. Eight other Dolphins were listed as questionable to play Sunday, including left tackle and safety T.J. McDonald, while was ruled doubtful after mi sing practice all week. The Bears come out of their bye healthy, with only depth defensive back on the shelf.Texans quarterback also drew a questionable tag on Friday after being limited in practice all week. For what it's worth, Watson indicated he'd definitely play in Week 6 against the Bills, so this may be a case of the team limiting his practice reps and planning on going with their starter barring an unexpected turn of events. is the backup in .The Falcons ruled out for Sunday's matchup with the Buccaneers. Freeman saw his first action since Week 1 against the Steelers last week, but he picked up a new foot injury in the game that will cost him a chance to play in Sunday's divisional tilt. steps back into the lead role for Bashaud Breeland Jersey Atlanta, with rookie serving as the team's No. 2 back. Coleman has rushed for 225 yards on 61 carries (3.7 yards per carry), while Smith has managed 21 carries for 80 yards this year. More on the NFL has played just once in the last three weeks for the , rushing for 20 yards on 10 carries in Week 4. It this week, though he's said before he's ready. This would be a great matchup for Cook, as the Cardinals have allowed a league-worst 712 rushing yards this season.The Redskins are dealing with multiple injuries to their top two running backs, with nursing shoulder, knee, and ankle i sues and dealing with knee and rib injuries. Both players were listed as questionable after being limited participants in practice all week. Both seem likely to suit up on Sunday. rumbled for 219 yards on only 15 carries in his team's blowout win over the Broncos last week, but he might not have the chance for an Patrick Peterson Jersey encore performance this week, as he's questionable to play with an ankle injury, and his status will likely depend on pregame workouts. Crowell is averaging 6.8 yards per carry this year while scoring five touchdowns in five games. Below, we'll go game by game to discu s what each final injury report means for the matchup and what you need to know before making your picks or setting your Fantasy lineups. at Vikings (-10)Cardinals:RB (back), OT D.J. Humphries (knee), OT Andre Smith (hamstring), G (shoulder), DE (knee), DT (foot)Vikings:OT (foot), DE (NIR), DE Tashawn Bowser (ankle), S (groin) OUT; RB Dalvin Cook (hamstring) QUESTIONABLEThe Cardinals are dealing with a shaky situation on the offensive line, with three starters limited in practice on Friday before drawing questionable tags. Smith and Iupati hadn't practiced all week, while Humphries was also limited on Thursday. Receiver (hamstring, back) is good to go after being upgraded to full practice on Friday, as are key defenders (wrist), (shoulder) and (shoulder). The Vikings are down key starters on both sides of the ball, with their left tackle and strong safety out for this matchup. Right tackle should kick over to the blindside, with rookie entering the starting lineup at Hill's normal spot. Jayron Kease and are candidates for bigger roles at safety this week. Cook was limited on Friday after practicing in full on Thursday but sounded optimistic about his chances of playing. at (PK)Chargers:WR (foot), DE (foot), LB (knee) OUT; OLB (groin) DOUBTFUL; OT (groin), OT (knee), K (quad) QUESTIONABLEBrowns Ameer Abdullah Jersey :WR (knee), WR (shoulder), LB (concu sion) OUT; LB (knee) QUESTIONABLEThe Chargers could be down two starting tackles again in this matchup with both Okung and Barksdale limited all week in practice. will fill in at kicker if Sturgis can't go. The Browns are hurting at receiver, with Higgins sidelined all week and Willies fracturing his collarbone in practice on Friday. and are set to receive the lion's share of the work at receiver, with and mixing in. Safety (knee) is good to go after practicing in full on Friday. (-3.5) at Bears:DB Marcus Cooper (hamstring) OUTDolphins:DE Cameron Wake (knee) DOUBTFUL; QB Ryan Tannehill (shoulder), WR (quad), WR (shoulder), TE A.J. Derby (foot), OT Laremy Tunsil (concu sion), DE (knee), OLB Andrew Booth Jr. Jersey (foot), CB (knee), S T.J. McDonald (foot) QUESTIONABLEThe Bears roll into this matchup healthy coming out of their bye, with rookie receiver (shoulder) practicing in full this week. Cornerback (hamstring) was upgraded to a full practice on Friday and is also good to go. Brock Osweiler is the No. 2 quarterback behind Tannehill, who's questionable to play after being downgraded to limited. Two receivers are also questionable, but Parker and Grant were both upgraded to full participants in practice on Friday. Tunsil, Branch, Allen and McDonald also practiced in full on Friday, meaning the team could have a lot of their questionable players available for this game. at (-1)Panthers:WR (ankle), LB (toe), LB (hamstring) OUT; TE (foot) QUESTIONABLERedskins:S (hamstring) OUT; G (calf) DOUBTFUL; RB Adrian Peterson (shoulder, knee, ankle), RB Chris Thompson (rib, knee), WR (ankle), WR (shoulder, knee), ( Kris Boyd Jersey heel), OT (knee), G (knee)The big news for the Panthers is that Greg Olsen, who practiced in full on Thursday and Friday, appears on track to see his first playing time since suffering a foot injury in the season opener. The star tight end has played in just eight games since the start of the 2017 season, while the Carolina pa sing game ranks 15th in DVOA this year, per Football Outsiders. Washington is dealing with a ton of injuries on offense, with one lineman likely out and two more questionable, though Williams and Scherff were both practicing in full on Friday. Peterson and Thompson were both limited all week while dealing with multiple injuries, as was Doctson. Crowder mi sed practice all week and seems unlikely to play, while Richardson was upgraded to a limited practice for the first time on Friday. at (-2.5)Colts:WR T.Y. Hilton (chest, hamstring), TE (hip), T (NIR), DE (hamstring), S (shoulder, groin, wrist), S (concu sion, neck) OUT; TE (shin, quad, ankle, knee), C (calf), DT (knee), LB (ankle), CB (knee), S (pec) QUESTIONABLEJets:WR (hamstring), CB (concu sion) OUT; LB (foot), CB (quad) DOUBTFUL; RB Isaiah Crowell (ankle), S (ankle/foot), S (hamstring) QUESTIONABLE Hilton and Doyle remain sidelined for the Colts, but Ebron was upgrade